解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Ongoing electrical activity was recorded from the axons of neurosecretory cells from the brain of 5th instar Rhodnius prolixus throughout the moulting cycle. Dramatic changes in both the frequency and pattern of electrical activity occur at specific times during the cycle, enabling the timing of release of neurohormon...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90314-5
更新日期:1980-06-02 00:00:00
abstract::Astrogliogenesis in the human fetal cerebellum was examined in 46 cerebella obtained from hysterotomy specimens ranging between 9 and 20 weeks of ovulation age. By correlating the results obtained by rapid Golgi and Golgi-Cox methods, the indirect immunofluorescence technique for glial fibrillary acidic protein, and e...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90280-2
更新日期:1980-05-26 00:00:00
abstract::L-[35S]Methionine was injected into the dorsal root ganglion (L5) of the adult rat, and migration of the neurofilament polypeptides (the triplet with molecular weights of 200,000, 160,000 and 68,000 daltons), alpha- and beta-tubulins and actin in the sciatic nerve and the dorsal root was quantitatively determined and ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90292-9
更新日期:1980-05-26 00:00:00
abstract::The rate and pattern of seizure development provoked by repeated electrical stimulation of the amygdala (kindling) was assessed in rats that had been pretreated with intracerebral injections of the selective catecholaminergic neurotoxin 6-hydroxy-dopamine. Rats with selective depletion of forebrain noradrenaline displ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90289-9
更新日期:1980-05-26 00:00:00
abstract::Horeradish peroxidase was injected at multiple sites in the mandibular and sublingual salivary glands in order to label the preganglionic salivatory neurons in the brain stem. The same injections resulted in retrograde labeling of the sympathetic and sensory neurons that project to these glands. Labeled fusiform and m...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90092-x
更新日期:1980-05-12 00:00:00
abstract::The dorsolateral quadrant of the lateral septal nucleus receives projections from both the ipsilateral and the contralateral fimbria. In the adult rat the effect of fimbrial lesions on synapse formation has been studied by a quantitative electron microscopic analysis of the various types of synapses present, using ele...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90010-4
更新日期:1980-05-05 00:00:00
abstract::The organization of globus pallidus (GP) projections was studied in cats using autoradiographic and horseradish peroxidase (HRP) techniques. Both methods confirmed the existence of a topographically organized projection to subthalamic nucleus (STN). Although all but the most caudal GP projects to STN, the heaviest pro...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90003-7
更新日期:1980-05-05 00:00:00
abstract::Extracellular recordings of action potentials were made from neurones antidromically identified as neurosecretory cells in the paraventricular and supraoptic nuclei of urethane-anesthetized female rats. Eighty-six neurones were examined for their responsiveness to 10 ng of angiotensin II (AII) injected into the third ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90048-7
更新日期:1980-04-28 00:00:00
abstract::The intra-axonal transport of horseradish peroxidase (HRP) has been used to trace the nodose ganglion and brain stem projections of a physiologically distinct nerve - the aortic depressor nerve - following electrophysiological identification. Tetramethyl benzidine (TMB) has been used as the substrate for demonstrating...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90553-3
更新日期:1980-04-21 00:00:00
abstract::Cholecystokinins in rat cerebral cortex were studied by radioimmunoassay using an antiserum specific for the COOH-terminus of CCK8. Total concentrations of immunoreactive CCK in cortex were 3-4 fold higher than in jejunum. Rat cerebral CCK was purified by immuno-affinity adsorption to the IgG fraction of CCK antisera ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90564-8
更新日期:1980-04-21 00:00:00
abstract::The extraction and utilization of sound level changes in acoustic-autonomic reflex systems were studied on a vasoconstriction response in the tail of nonanesthetized rats. The vasoconstriction was found to depend on sound level and changes of level in the following ways. (a) It increased as a linear function of sound ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90555-7
更新日期:1980-04-21 00:00:00
abstract::Plasma prolactin (PRL) levels were investigated in chronically catheterized control, sham-lesioned, and amygdala (AMYG)-lesioned rats under a variety of conditions. Ovariectomized (OVX) rats injected with 0.5 mg of polyestradiol phosphate (PEP) exhibited a circadian rhythm of PRL secretion characteristic of proestrus ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90202-4
更新日期:1980-04-14 00:00:00
abstract::Cerebellar explants derived from neonatal mice were exposed to cytosine arabinoside, an inhibitor of DNA synthesis. Following such exposure, the cortical regions of the explants contained numerous closely packed large neurons with few intervening elements and without lamination. The surviving large cortical neurons in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90984-1
更新日期:1980-03-31 00:00:00
abstract::The effect of repetitive stimulation of the locus coeruleus (LC) on the discharge rate of spontaneously active neurons of the visual, rostral and cingulate cortex was investigated in untreated and catecholamine-depleted rats under chloral hydrate anesthesia. In untreated animals, the inhibitory transsynaptic effects p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90251-6
更新日期:1980-03-17 00:00:00
abstract::The relationship between the dorsal raphe neurons projecting to the caudate-putamen and those projecting to the substantia nigra was investigated using a fluorescent retrograde double labeling technique in the rat. The majority of the dorsal raphe neurons projecting to the substantia nigra were found to project also t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90250-4
更新日期:1980-03-17 00:00:00
abstract::Unitary discharges in the efferent ciliary nerves were studied in cervical sympathectomized rabbits. In all, 279 units were recorded and categorized, except 7 units, into the following 3 types from their responses to photic and other stimuli, i.e. type A (170 units), type B (42 units) and type C (60 units). Type A uni...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90254-1
更新日期:1980-03-17 00:00:00
abstract::Intracellular recordings were obtained from CA1 pyramidal neurons in obliquely cut in vitro hippocampal slices. Recurrent IPSPs were elicited by antidromic stimulation of alvear fibers. The mechanisms by which IPSPs depress pyramidal cell excitability were investigated. Recurrent IPSPs could be reversed in sign by sma...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91068-9
更新日期:1980-03-10 00:00:00
abstract::The total number of neurosensory cells in the mouse vomeronasal organ was estimated during postnatal development by counting the cell density and measuring the total volume of the neurosensory cell layer. There is a 43% increase in neurosensory cell number between 1 and 4 months of age, followed by a 21% fall in cell ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90675-7
更新日期:1980-03-03 00:00:00
abstract::The connectivity of the stellate ganglion of Octopus was investigated using cobalt and horseradish peroxidase (HRP) tracers applied to severed preganglionic and postganglionic nerves. Centripetal cells, defined as cells in the ganglion which send their axons back toward the brain, were discovered by both methods. Appl...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90583-1
更新日期:1980-02-17 00:00:00
abstract::Unilateral destruction of the entorhinal area in the rat results in the proliferation of a pathway from the surviving contralateral entorhinal area to the fascia dentata denervated by the lesions (the crossed temporodentate pathway). The present study analyzes the point of entry of these reinnervating fibers into the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90464-3
更新日期:1980-02-10 00:00:00
abstract::This study examines projection to the cerebellar flocculus of eye movement-related neurons in the median and paramedian part of the cat pontine tegmentum between the trochlear and the abducens nucleus. They were identified by rhythmic activity related to horizontal vestibular nystagmus induced by sinusoidal rotation. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90465-5
更新日期:1980-02-10 00:00:00
abstract::The effects of the epileptogenic agent, penicillin, on excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs) were studied in the hippocampal in vitro slice preparation. The actions of penicillin were compared to those of bicuculline, an antagonist of gamma-aminobutyric acid. Neither substance enhanced mo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90119-5
更新日期:1980-02-03 00:00:00
abstract::Ciliary ganglion neurons from chick embryo were grown in cell culture following enzymatic and mechanical dissociation. The culture conditions necessary for long-term (greater than 21 days) survival of the isolated neurons were investigated. Neurons could be cultured with and without non-neural cells by adjusting the c...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90127-4
更新日期:1980-02-03 00:00:00
abstract::Two high molecular weight surface glycoproteins of cerebellar cells which are selectively labeled by lactoperoxidase-catalyzed iodination of monolayer cultures from the developing mouse cerebellum, have been identified and partially characterised. Both molecules, called peak 2 and peak 3 proteins, were the major glyco...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91197-x
更新日期:1980-01-27 00:00:00
abstract::In order to elucidate the functional role of nicotinic receptors in the hypothalamus, the drug-induced release of noradrenaline from hypothalamic synaptosomes was studied utilizing [3H]noradrenaline ([3H]NA). The release of [3H]NA from synaptosomes was significantly increased with an increase of the dose of nicotine, ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91194-4
更新日期:1980-01-27 00:00:00
abstract::Intraventricular injections of kainic acid were used to destroy the hippocampal CA3-CA4 cells, thus denervating the inner third of the molecular layer of the fascia dentata and stratum radiatum and stratum oriens of area CA1. The responses of intact afferents to such lesions were then examined histologically. The hipp...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90825-2
更新日期:1980-01-20 00:00:00
abstract::Atropine (5 nM to 5 muM), but not D-tubocurarine or hexamethonium, enhanced the release of acetylcholine (ACh) from rat brain cortical slices exposed to high K+. The enhancement was dose-dependent, and it could be partially antagonized by oxotremorine (50-500 muM) or by dibutyryl or 8-bromo-cyclic GMP (1 mM), but not ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90836-7
更新日期:1980-01-20 00:00:00
abstract::It is known that transmitter release depends upon the entry of calcium ions into the synaptic terminal. Mitochondria have been suggested to play a key role on the regulation of intracellular Ca2+ concentration, thereby influencing transmitter liberation and synaptic transmission. Here we report the stimulatory effect ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90618-6
更新日期:1980-01-13 00:00:00
abstract::Repeated administration of high doses of methamphetamine produced long-term decreases in dopamine (DA) levels and in the number of DA uptake sites in the rat striatum. These two effects were dose-related and did not appear to be due to the continued presence of drug in striatal tissue. Long-lasting depletions induced ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91265-2
更新日期:1980-01-06 00:00:00
abstract::Repetitive stimulation of an axon in the right visceropleural connective to the abdominal ganglion of Aplysia californica produces post-tetanic potentiation (PTP) of a unitary monosynaptic EPSP recorded from cell R15. PTP decays within one half hour following cessation of repatitive stimulation. Stimulation of the lef...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91262-7
更新日期:1980-01-06 00:00:00
abstract::Choline molecules are needed for the synthesis of acetylcholine and phospholipids in the mammalian brain. An enzymatic activity capable of forming lecithin (phosphatidylcholine) from the step-by-step methylation of phosphatidylethanolamine is identified in the bovine brain. This enzyme(s), phosphatidylethanolamine-N-m...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90447-5
更新日期:1979-12-28 00:00:00
abstract::A push-pull perfusion technique was employed for in vivo study of adenosine 3',5'-monophosphate (cAMP) and guanosine 3',5'-monophosphate (cGMP) in the rat caudate nucleus. Addition of dopamine to the perfusion fluid elicited dose-dependent increases of both cAMP and cGMP perfusate concentrations. In separate experimen...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90495-5
更新日期:1979-12-21 00:00:00
abstract::The solubilized rat central nervous system (hypothalamic) nicotinic cholinergic receptor and the Torpedo nicotinic cholinergic receptors are immunologically similar and show greater than 60% immunologic cross-reactivity using a double-antibody technique. Antibodies to the Electrophorus and Torpedo receptors also decre...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90700-5
更新日期:1979-12-14 00:00:00
abstract::Experiments were carried out to determine if stimuli which augment preganglionic nerve activity to sympathetic neurons, and thereby cause trans-synaptic induction, increase the retrograde transport of nerve growth factor (NGF). It was found that nerve activity had no effect on retrograde transport of [125I]NGF. It was...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90701-7
更新日期:1979-12-14 00:00:00
abstract::The changes in the excitability of lumbosacral spinothalamic neurons produced by activating afferents in the trigeminal nerve using electrical or mechanical stimuli was investigated in cats anesthetized with alpha-chloralose. In most spinothalamic neurons, weak electrical stimuli or step indentations of the skin of th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90776-5
更新日期:1979-11-16 00:00:00
abstract::The participation of amygdaloid and striatal structures in the various signs of morphine withdrawal syndrome (MWS) has been investigated using two complementary approaches: intracerebral application of naloxone in various nuclei of dependent rats and effects of various lesions and transections on systemically induced ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90915-6
更新日期:1979-11-09 00:00:00
abstract::Differential circadian rhythms in 5-HT levels were found in the hypothalamus and pineal (but not in the cortex, hippocampus or midbrain) in ferrets kept in either long (14 h light/10 h dark) or short (8 h light/16 h dark) photoperiods. 5-HT decreased during the first 6 h of illumination in all areas examined from anim...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90986-7
更新日期:1979-11-02 00:00:00
abstract::A highly specific antibody to alpha-melanocyte stimulating hormone (alpha-MSH) was used to histochemically localize and biochemically identify and quantitate alpha-MSH immunoreactivity in nerve fibers and cell bodies of the rat brain. alpha-MSH-like immunoreactivity was contained in fibers throughout the brain. The di...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90873-4
更新日期:1979-10-26 00:00:00
abstract::Prominent cellular responses to axonal interruption include enhanced synthesis of RNA and protein in the neuronal perikaryon, and proliferation of reactive Schwann cells. Since morphine has been shown to significantly depress cellular metabolism, we examined its effect on these and other reparative responses underlyin...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)91010-2
更新日期:1979-10-19 00:00:00
abstract::The 'commissural' innervation of the dentate gyrus molecular layer has been analyzed in normal adult rats and in those in which the ipsilateral entorhinal cortex had been removed by aspiration at 14 days post-natal. This ablation severely deafferents the distal two-thirds of the molecular layer and induces 'sprouting'...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90512-2
更新日期:1979-10-12 00:00:00